Low-cost SARS-CoV-2 Vaccine Homogenization System for Pfizer-BioNTech COVID-19 vials

Jose Lima, Luísa Rocha, Cláudia Rocha, Paulo Costa


The current SARS-CoV-2 pandemic has been affecting all sectors worldwide, and efforts have been targeting the enhancement of people's health and labour conditions of collaborators belonging to healthcare institutions. The recent vaccines emerging against COVID-19 are seen as a solution to address the problem that has already killed up to two million people. The preparation of the Pfizer-BioNTech COVID-19 vaccine requires a specific manipulation before its administration. A correct homogenization with saline solution is needed and, therefore, a manual process with a predefined protocol should be accomplished. This action can endanger the pharmacists and technicians’ ergonomics on account of the repetitive movement of the process. This paper proposes a low-cost and prompt development prototype to perform the vials’ homogenization in an autonomous approach allowing to redirect these healthcare workers to other tasks. Moreover, a contactless start order process was implemented to avoid contact with the operator and, consequently, the contamination. The prototype was tested and is being applied during the preparation of the COVID-19 vaccines at hospital pharmacy of Centro Hospitalar de Vila Nova de Gaia/Espinho, E.P.E., Portugal. It can be easily replicated since the source files to assemble it are provided by the authors.


SARS-CoV-2 Vaccine; COVID-19; Homogenization; Pharmacy preparations and compounding

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DOI: http://doi.org/10.11591/ijra.v10i4.pp%25p


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